Publications

2019

  • Chunguang Ren, Quaning Yuan, Martha Braun, Bjorn Petri, Jiasheng Zhang, Paul Kubes, Zhaoxia Sun, Franck Polleux, Erdem Karatekin*, Wenwen Tang*, Dianqing
    Wu*, “Cell Attachment-Induced Local Increase in Plasma Membrane Curvature Is a Symmetry-Breaking Cue that Initiates Neutrophil Cytoskeleton Polarization”, accepted, Dev. Cell.
  • Natasha R. Dudzinski, Zhenyong Wu*, Erdem Karatekin*, “A Nanodisc-Cell Fusion Assay with Single-Pore Sensitivity and Sub-millisecond Time Resolution”, Methods Mol Biol. 2019;1860:263-275. doi: 10.1007/978-1-4939-8760-3_17.

2018

  • Erdem Karatekin and James E. Rothman, FEBS Letters Special Issue on Exocytosis and Endocytosis. Editorial. 2018, 592:3477-3479. doi: 10.1002/1873-3468.13274.
  • Erdem Karatekin*, “Toward a unified picture of the exocytotic fusion pore”, 2018; 592:3563-3585. doi: 10.1002/1873-3468.13270. Epub 2018 Oct 26.

2017

  • Lu Ma, Yiying Cai, Yanghui Li, Junyi Jiao, Zhenyong Wu, Ben O’Shaughnessy, Pietro De Camilli*, Erdem Karatekin*, Yongli Zhang*, “Single-molecule force spectroscopy of protein-membrane interactions.”, eLife 2017;6:e30493 doi: 10.7554/eLife.30493
  • Z. Wu, S. Thiyagarajan, B. O’Shaughnessy and E. Karatekin*, “Regulation of exocytotic fusion pores by SNARE protein transmembrane domains”, Front. Mol. Neurosci. 2017 doi: 10.3389/fnmol.2017.00315
  • H. Mostafavi, S. Thiyagarajan, B. S. Stratton, E. Karatekin, J. M. Warner,
    J. E. Rothman*    , and B. O’Shaughnessy*, “Entropic forces drive self-organization and membrane fusion by SNARE proteins“, PNAS 2017  doi/10.1073/pnas.1611506114
  • Z. Wu, O. Bello, S. Thiyagarajan, S. M. Auclair,  W. Vennekate, S. S. Krishnakumar, B. O’Shaughnessy and E. Karatekin*, “Dilation of fusion pores by crowding of SNARE proteins”, eLife 2017;10.7554/eLife.22964.

2016

  • Z. Wu, S. M. Auclair, O. Bello, W. Vennekate, N. R. Dudzinski, S. S. Krishnakumar, and E. Karatekin*, “Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains”, Scientific Reports, 6, 27287, 2016.
  • W. Xu, B. Nathwani, C. Lin, J. Wang, E. Karatekin, F. Pincet, W. Shih*, and J. E. Rothman*,”A programmable DNA origami platform to organize SNAREs for membrane fusion”, J. Amer. Chem. Soc. 138:4439-4447, 2016.
  • J. Nikolaus*, E. Karatekin*, “SNARE-mediated fusion of single proteoliposomes with tethered supported bilayers in a microfluidic flow cell monitored by polarized TIRF microscopy”, J. Vis. Exp. (114), e54349, doi:10.3791/54349 (2016).
  • B. S. Stratton, J. M. Warner, Z. Wu, J. Nikolaus, G. Wei, E. Wagnon, D. Baddeley, E. Karatekin*, and B. O’Shaughnessy*, “Cholesterol increases the openness of SNARE-mediated flickering fusion pores“, Biophys. J. 110:1538-1550, 2016.
2015
  • C. Laplante, J. Berro, E. Karatekin, A. Hernandez-Leyva, R. Lee, and T. D. Pollard*, “Three Myosins Contribute Uniquely to the Assembly and Constriction of the Fission Yeast Cytokinetic Contractile Ring” Current Biology, 25, 1955-1965, 2015.
2014
  • M. R. Stachowiak, C. Laplante, H. F. Chin, B. Guirao, E. Karatekin, T. D. Pollard, and B. O’Shaughnessy*, Mechanism of Cytokinetic Contractile Ring Constriction in Fission Yeast, Dev. Cell, 29, 547–561, 2014.
2013
  • T. Doan, J. Coleman, K. A. Marquis, B.M. Burton, E. Karatekin*, and D. Z. Rudner*, FisB mediates the final membrane fission event during sporulation in Bacillus Subtilis, Genes Dev., 27, 322-334, 2013.
2012
  • E. Karatekin*and J.E. Rothman, “Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells”. Nature Protocols, 7:903-920, 2012.
2011
  • Smith MB, Karatekin E, Gohlke A, Mizuno H, Watanabe N, and Vavylonis D. Interactive, computer-assisted tracking of speckle trajectories in fluorescence microscopy: application to actin polymerization and membrane fusion. Biophys. J. 101:1794-1804, 2011.
  • Meunier A, Jouannot O, Fulcrand R, Fanget I, Bretou M, Karatekin E, Arbault S, Guille M, Darchen F, Lemaître F, and Amatore C. Coupling amperometry and total internal reflection fluorescence microscopy at ITO surfaces for monitoring exocytosis of single vesicles. Angew. Chem. Int. Ed., 50:5081-5084, 2011.
2010
2009
  • Warner JM, Karatekin E, and O’Shaughnessy B. Model of SNARE-mediated membrane adhesion kinetics. PLoS One 4(8):e6375, 2009.
2008
  • Karatekin E, Tran S, Huet S, Fanget I, Cribier S, and Henry JP. A 20 nm step toward the cell membrane preceding exocytosis may correspond to docking of tethered granules. Biophys. J. 94:2891-2905, 2008.
pre-2008
  • Tran VS, Huet S, Fanget I, Cribier S, Henry JP, and Karatekin E. Characterization of sequential exocytosis in a human neuroendocrine cell line using evanescent wave microscopy and `virtual trajectory’ analysis. Eur. Biophys. J. 37:55-69, 2007.
  • S. Huet, E. Karatekin*, V. S. Tran, I. Fanget, S. Cribier and J.-P. Henry*, “Analysis of transient behavior in complex trajectories: application to secretory vesicle dynamics.” Biophys. J. 91, 3542-3559 (2006).
  • N. Borghi, F. Brochard-Wyart, E. Karatekin, and I. Derényi, “Giant vesicles: Transient pores and tube extraction”. Proc. Int. School of Physics “Enrico Fermi”. Course CLV, F. Mallamace and H. E. Stanley (Eds.); IOS Press, Amsterdam (2004).
  • L. Zecca*, A. Stroppolo, A. Gatti, D. Tampellini, M. Toscani, M. Gallorini, G. Giaveri, P. Arosio, P. Santambrogio, R. G. Fariello, E. Karatekin, M. H. Kleinman, N. Turro, O. Hornykiewicz, and F. A. Zucca, “The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging”. Proc. Natl. Acad. Sci. USA, 101, 9843-9848 (2004).
  • S. Tran, A.-M. Marion-Audibert, E. Karatekin, S. Huet, S. Cribier, K. Guillaumie, C. Chapuis, C. Desnos, F. Darchen, and J.-P. Henry*, “Serotonin secretion by human carcinoid BON cells”, Ann. N.Y. Acad. Sci., 1014, 1–10 (2004).
  • P.-H. Puech, N. Borghi, E. Karatekin, and F. Brochard-Wyart*, “Line Thermodynamics: Adsorption at a Membrane Edge”, Phys. Rev. Lett., 90, 128304 (2003).  Highlighted as a Search and Discovery article: “Experiments Investigate the Behavior of Pores in Artificial Vesicles: Twenty-first century experimental techniques combine with 19th century theory to explore how cell membranes behave when breached.” Physics Today, 56 (5):22-24, May 2003.
  • E. Karatekin, O. Sandre, H. Guitouni, N. Borghi, P.-H. Puech, and F. Brochard-Wyart*, “Cascades of Transient Pores in Giant Vesicles: Line Tension and Transport”, Biophys. J., 84, 1734-1749 (2003).
  • E. Karatekin, O. Sandre, and F. Brochard-Wyart*, “Transient Pores in Vesicles”, Polym. Int., 52, 486-493 (2003).
  • E. Karatekin, B. O’Shaughnessy*, and N. J. Turro, “The Photocopy Method: Measuring Living Chain Distributions in Radical Polymerization”, Macromol. Symp., 182, 81-101 (2002).
  • E. Karatekin, M. S. Landis, G. Lem, B. O’Shaughnessy*, and N. J. Turro, “Photocopying Living Chains. 2. Time-Dependent Measurements”, Macromolecules, 34, 8202-8215 (2001).
  • E. Karatekin, M. S. Landis, G. Lem, B. O’Shaughnessy*, and N. J. Turro, “Photocopying Living Chains. 1. Steady-State”, Macromolecules, 34, 8187-8201 (2001).
  • N. J. Turro*, M. H. Kleinman, and E. Karatekin, “Electron Spin Polarization and Time-Resolved Electron Paramagnetic Resonance: Applications to the Paradigms of Molecular and Supramolecular Photochemistry”, Angew. Chem. Int. Ed., 39, 4436-4461 (2000).
  • D. Sulzer*, J. Bogulavsky, K. E. Larsen, G. Behr, E. Karatekin, M. H. Kleinman, N. Turro, D. Krantz, R. H. Edwards, L. A. Greene, L. Zecca, “Neuromelanin Biosynthesis is Driven by Excess Cytosolic Catecholamines not Accumulated by Synaptic Vesicles”. Proc. Natl. Acad. Sci. USA, 97, 11869-11874 (2000).
  • E. Karatekin, B. O’Shaughnessy, and N. J. Turro*, “Time Resolved EPR: A Novel Method for Studying Living Chains”, Macromolecules, 31, 7992-7995 (1998).
  • E. Karatekin, B. O’Shaughnessy*, and N. J. Turro, “Kinetic Isolation of Macroradicals”, Macromolecules, 31, 4655-4658 (1998).
  • E. Karatekin, B. O’Shaughnessy*, and N. J. Turro, “Kinetic Isolation of Persistent Radicals and Application to Polymer-Polymer Reactions”, J. Chem. Phys., 108, 9577-9585 (1998).